This causes a high BUN-to-creatinine ratio. Dehydration generally causes BUN levels to rise more than creatinine levels. See if treatment of your kidney disease is working.Ĭheck for severe dehydration. See if your kidney disease is getting worse. See if your kidneys are working normally. A BUN-to-creatinine ratio can help your doctor check for problems, such as dehydration, that may cause abnormal BUN and creatinine levels. Blood urea nitrogen (BUN) and creatinine tests can be used together to find the BUN-to-creatinine ratio (BUN:creatinine). The level of creatinine in your blood also tells how well your kidneys are working-a high creatinine level may mean your kidneys are not working properly. A low BUN level can occur normally in the second or third trimester of pregnancy.īlood urea nitrogen to creatinine ratio (BUN:creatinine)Ī BUN test may be done with a blood creatinine test. Liver disease or damage can lower your BUN level. ![]() Heart failure, dehydration, or a diet high in protein can also make your BUN level higher. If your kidneys are not able to remove urea from the blood normally, your BUN level rises. Urea is made in the liver and passed out of your body in the urine.Ī BUN test is done to see how well your kidneys are working. Urea is made when protein is broken down in your body. He was seen emergently at this hospital for a recheck, which showed continued increase in creatinine to 2.09 mg/dL (185 μmol/L) and with a blood urea nitrogen of 13 mg/dL.Health Library Skip Navigation Top of the page Blood Urea Nitrogen (BUN) Test Test OverviewĪ blood urea nitrogen (BUN) test measures the amount of nitrogen in your blood that comes from the waste product urea. The age-based normal value of creatinine for this patient is ∼0.15 to 0.3 mg/dL (15–30 μmol/L). Because of concern for possible hyponatremia, laboratories were checked, which showed a serum creatinine 1.29 mg/dL (114 μmol/L) with repeat creatinine 1.61 mg/dL (142 μmol/L). He had been tolerating the custom formula with no such issues. The only other formula that was somewhat agreeable was Alimentum (ready to feed) because it only caused constipation. The infant had been tried on multiple other formulas in conjunction with his pediatrician because of worsening of reflux, constipation, increased fussiness, and nasal congestion. 7 The mother introduced this custom formula without the pediatrician’s knowledge because of concerns related to previous formula intolerance. 7 This formula consists of 3 3/4 cup chicken broth, 2 oz beef liver, 5 tablespoons lactose (brand NOW), 1/4 teaspoon Bifidobacterium infantis, 1/4 cup homemade liquid whey, 1 tablespoon coconut oil, 1/2 teaspoon cod liver oil, 1 teaspoon sunflower oil, 2 teaspoons olive oil, and 1/4 teaspoon acerola powder (brand NOW). He was seen by his pediatrician for his 4-month well-child visit, where his parents informed his physician that they had started him on a custom formula named Weston Price Beef Liver Formula. We highlight the importance of in-depth nutrition assessments and education on the health risks associated with improper formula selection.Ī 4-month-old boy, born at 31 weeks (corrected gestational age 8 weeks) with a 5-week NICU stay, with gastroesophageal reflux, presented to the hospital emergency department for evaluation of elevated serum creatinine. ![]() Within 12 hours of stopping the infant’s homemade formula and providing intravenous fluids, the infant’s creatinine normalized. After in-depth evaluation of nutritional intake, there was a suspicion for high creatine load of the infant’s homemade formula, which was composed of beef liver and various unregulated nutritional powders. In this report, we describe the case of excessive dietary creatine intake in an infant who presented with elevated creatinine while otherwise appearing healthy and having normal cystatin C. With greater accessibility to internet-based medical advice (licensed or unlicensed), parents and families have more chances to be exposed to opportunistic websites and opinions that may provide harmful information. Standard infant formulas and breastmilk generally fall within a select range of creatine content. ![]() The expanding field of infant formula selection in recent history has given many options for parents who are unable to provide breastmilk. Yet, it is a marker that can only provide estimations of kidney function because it can be influenced by other factors, such as dietary intake. Serum creatinine is typically used to evaluate kidney function.
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